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K562-Fluc-Puro/CyBCMA-Neo

Species: Human 

Cell Type: Chronic Myelogenous Leukemia 

Transgenes:  Firefly luciferase (Fluc; Luc2) 

Cynomolgus macaque B cell maturation antigen (CyBCMA) 

Selection Gene:  Puromycin resistance (Puro) 

Neomycin resistance (Neo) 

 

Description 

The K562-Fluc-Puro/CyBCMA-Neo cell line stably expresses firefly luciferase and cynomolgus macaque BCMA. The cells are designed for in vitro and in vivo studies of CyBCMA. Parental K562-Fluc-Puro cells (Imanis #CL171) can be used as a negative control. 

Parental K562-Fluc-Puro cells (Imanis #CL171) cells were transduced with a CyBCMA-encoding lentivirus. A high CyBCMA expressing population was generated by selection using a methylcellulose based semi-solid medium.  

This cell line has been tested for mycoplasma contamination and is certified mycoplasma free. 

The parental K562 cell line was licensed and purchased directly from ATCC*. 

Replication Competent Lentivirus (RCL) Test (including a test report) is available for this cell line at an added cost. Contact usto learn more. 

*The ATCC trademark and trade name and any and all ATCC catalog numbers are trademarks of the American Type Culture Collection. 

 

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With quality reagents, services, and support, we have you covered at all stages of your study. Our expert scientists can help you select the best reagents for your needs and offer tips to optimize your experiments and achieve superior results. Our wide-range of reporter gene and oncolytic virus reagents undergo rigorous quality control testing so you can be confident in the quality of the products you receive. And with our competitive prices, you can complete your study for less.

  • “Our group has, and continues to, use NIS as a noninvasive reporter for cell transplantation studies in mice and in pigs. Imanis has provided expert technical and analytical support for this research, and has allowed us to publish our research in high impact journals, including Science Translational Medicine.” – Dr. Raymond Hickey, Mayo Clinic

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Use Fewer Animals

Our Reduction Campaign

At Imanis, we are committed to promoting the practice of the 3Rs in animal research. Learn how we are decreasing the use of animals and research as well as saving up to 15% on your orders. Continue reading...

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